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Potential risk factors for TEAS in depression include BD-I illness subtype, rapid-cycling course, co-morbid substance use disorder (SUD), prior history of TEAS, more prior depressive episodes, previous suicide attempt, baseline mixed features (concurrent symptoms of manic pole), and family history of BD.[169,172] Given the clinical importance of an antidepressant-induced switch in BD management,[173] we offer the following suggestions to prevent and manage such instances:[20,163,164,174,175] Screen for known risk factors, including a history of TEAS, before initiating antidepressants in BD

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Most researchers start at lower doses and gradually increase to allow the body to adapt and minimize initial side effects