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Side effects and safety When considering the side effects and safety of tirzepatide, marketed as Mounjaro and Zepbound, its important to note the common and serious adverse reactions patients may experience

Once your glucose is above 4.0 mmol/L, have a starchy snack if your next meal is more than an hour away

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usually subsides within 2-4 weeks at each dose level Diarrhea tends to be mild and self-limiting Constipation often manageable with increased fibre and water intake Decreased appetite this is partly how the medication works, but extreme appetite suppression should be reported to your doctor Injection site reactions mild redness or itching at the injection site Serious Side Effects (rare but important) Pancreatitis: Seek immediate medical attention if you experience severe, persistent abdominal pain radiating to the back Gallbladder disease: Rapid weight loss can increase gallstone risk Hypoglycaemia: Primarily a risk when combined with insulin or sulfonylureas Thyroid C-cell tumours: Observed in rodent studies