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Furthermore, with a run-in phase of a low-calorie diet, total weight loss of up to 12.5 kg can be achieved (of which half [6.2%] was observed during the liraglutide 3.0 mg treatment period) in subjects with obesity (176)

Clinical trial data suggest that gastrointestinal side effects, including any reflux symptoms, typically improve over time as patients develop tolerance to the medication

2.0 mg) may increase the intensity of side effects for some patients, serious injuries like gastroparesis have been reported at all dosage levels , ****including at the lowest doses

Such practices are essential to ensure patient safety and well-being while navigating the complexities of obesity management and its potential psychiatric implications