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Patients using both should undergo routine monitoring of lipid panels, hemoglobin A1C, hematocrit, and blood pressure to ensure both medications are contributing to improved metabolic health rather than working at cross-purposes

In the SURMOUNT-1 trial , participants receiving the highest dose of Tirzepatide achieved average body weight reductions of 20.9% over 72 weeks, compared to the 14.9% reduction observed with Semaglutide in the STEP-1 trial

These clinical data signaled the impending arrival of an expanding armamentarium of obesity medications

Consider professional support if: MD-supervised programs, like those at MD Total Wellness, combine medications, nutrition counseling, and lifestyle support to achieve lasting weight loss success
