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21,22 Although clear protective benefits in diabetic retinopathy development and impact on disease progression remain under investigation, GLP-1RAs have been shown to reduce complications from chronic diabetes, such as retinal vein occlusion and cardiovascular disease

This effect translates to a low risk of hypoglycemia in patients with type 2 diabetes treated with GLP-1RAs [42]

There is also the issue of price pressures from both public health systems and private insurers as the GLP-1 class continues to grow and more generic versions are introduced