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Description
ELIXA trial included patients with recent cardiovascular event (patients with acute coronary syndrome 180 days before randomization), and although there was no benefit in MACE reduction in lixisenatide treated patients compared to placebo, results revealed cardiovascular safety of lixisenatide in this specific high risk population (38, 40)

And decreasing the risk of that starts right now, not waiting til we break

Lilly argues its drug holds a practical edge, as unlike the semaglutide pill, which must be taken first thing in the morning on an empty stomach, orforglipron can be taken at any time of day without food or water restrictions

Tirzepatide has an additional mechanism as a dual GIP and GLP-1 agonist, meaning it activates two separate gut hormone receptors simultaneously
