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Description
A.HissaM

Tirzepatide is optimized for GIP and GLP-1 receptor engagement with minimal glucagon-receptor activity, while retatrutide retains GLP-1 and GIP affinity but introduces substitutions that restore meaningful glucagon-receptor binding

Glucagon-like peptide-1 (GLP-1) receptor agonists represent a class of medications originally developed for type 2 diabetes management, with some now approved for chronic weight management

Alimentary Pharmacol
