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296 , E291E299 (2008)
The primary concern, rapid drops in blood sugar from GLP-1 therapy can temporarily worsen existing DR, which is why it has been highlighted in research

In the EU, the procedure is less centralized and despite the fact that only a single application is submitted via a common electronic platform (Clinical Trial Information System, CTIS), national authorities in each of the member countries must issue separate permissions

In the brain, Gipr is found in the cerebral cortex, hippocampus, olfactory bulb as well as in the hypothalamus and the hindbrain (155157)