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Main text Within this review, we provide an overview of the intricate interplay between chronic inflammation of the adipose tissue and the hypothalamus and the development of obesity

Clinical Significance: The 2025 updates reaffirm that while HbA1c remains central, a one-number-fits-all strategy is outdated

This article explains whether muscle loss can occur, why it happens, and how to protect lean mass through protein intake, resistance training, and structured nutrition strategies.

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