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While semaglutide suppresses hunger, undereating can impair workout quality and slow metabolic adaptation, so maintaining proper nutrition remains essential even when appetite is suppressed

Clinical trials show semaglutide's weight loss benefits come primarily from reduced appetite and slower digestion, not meal timing itself

Safety of ethyl lauroyl arginate (E 243) as a food additive in the light of the new information provided and the proposed extension of use

Acknowledgements We are grateful to Health Data Science Center, National Cheng Kung University Hospital, for providing administrative and technical support