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Dividing the drug candidates by condition type, 129.2 million could benefit from semaglutide for weight control, 35 million could use it to help manage diabetes and 8.9 million might use it to prevent heart disease, the Boston team said

Although the sample size was small with only 48 total participants randomized across the two treatment conditions, the randomized, double-blinded, experimental design provides some compelling preliminary evidence that semaglutide might reduce alcohol craving and the amount of alcohol consumed on drinking days in people with alcohol use disorder not actively seeking treatment

Most patients report feeling only mild pressure or no pain at all, especially after their first or second injection when anxiety decreases

12, 2025 from Pan, J., Cen, L., Chen, W., et al