statins and glp-1 aggravate insulin resistance through reduced blood glucagon-like peptide-1 levels in a microbiota-dependent manner: Cell Metabolism The Statin–GLP-1 Problem: The Gut
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While challenges with adherence, side effects, and weight regain upon discontinuation have prompted the search for additional strategies, targets like GLP-1R, GIPR, and GDF8 (Myostatin) still remain the most highly relevant and active areas of research for developing effective obesity treatments
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