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Description
Having demonstrated that GLP-1MK-801 and GLP-1inactive MK-801 display comparable pharmacokinetic properties in vitro, we next assessed their respective in vivo efficacies against the parent GLP-1 analogue in DIO mice
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They make pancreatic beta cells produce insulin, stop glucagon from being released, slow the emptying of the stomach, and lower appetite through paths in the central nervous system

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