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NCT05929066 is one registered obesity trial

Key Takeaway: On GLP-1 medications, reduce training volume by 20 to 30 percent, add an extra rest day per week, and maintain intensity to protect the muscle-preservation signal

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Preclinical studies consistently demonstrate that GLP-1R activation reduces drug-seeking behaviors, cue-induced reinstatement, and consumption of substances with high addictive potential, including alcohol, nicotine, opioids, stimulants, and palatable food
