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Description
Subsequent OXM structureactivity relationship studies identified a series of analogues with superior potency relative to the native hormone [85]

The actions of GLP-1 to stimulate insulin and inhibit glucagon secretion, together with its inhibitory effects on food intake and gastric emptying, spurred considerable effort in development of GLP-1based therapeutics
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[DOI] [PMC free article] [PubMed] [Google Scholar] 79.Ren Q, Chen S, Chen X, Niu S, Yue L, Pan X, Li Z, Chen X