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The SUSTAIN-6 CVOT [67], performed in 3,297 patients with T2DM and ASCVD/CKD, has shown that compared to placebo, semaglutide was associated with increased retinopathy complications (3.0% versus 1.8%

According to the Centers for Disease Control and Prevention National Diabetes Statistics Report 2022, more than 130 million individuals in the United States have diabetes or prediabetes
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Since dry mouth can change tastes and accentuate metallic tastes, and since dry mouth is a known side effect of semaglutide, it might explain GLP-1 Tongue
