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[16] These medications work through multiple complementary mechanisms: they enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release from alpha cells, slow gastric emptying to reduce postprandial glucose excursions, and act on central nervous system pathways to promote satiety and reduce appetite

Semaglutide, on the other hand, targets only one hormone to produce its effects in experimental studies

The Wegovy pill offers the same active ingredient in an oral form for those who wish to avoid injections

For best results with retatrutide, stay connected with your care team, report side effects, and stay up to date with guidance