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In patients with pre-existing conditions, the damage can accelerate kidney failure and result in dialysis or transplant needs

The primary estimand evaluated the treatment effect of the primary endpoint for all randomised participants, irrespective of adherence to trial product, initiation of non-randomised insulin treatment or addition of other non-insulin glucose-lowering medications (for more than 2 weeks) (i.e

However, compounded drugs pose a higher risk to patients than FDA-approved drugs because compounded drugs do not undergo FDA premarket review for safety, effectiveness or quality