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Pendulum GLP-1 Probiotic (Professional Strength) 30 capsules

The addition of oligofructose as a prebiotic to the diet in ob/ob mice significantly increases plasma GLP-1, colonic L cell abundance, and colon proglucagon mRNA levels 73,74 , and GLP-2R antagonism blunts the anti-inflammatory effects of this prebiotic treatment 73

Benefit of dual therapy with GLP-1 RA and SGLT2i on renal outcomes in type 2 diabetes

Animal studies showed increased rates of pregnancy loss, reduced birth weight, and some developmental abnormalities when tirzepatide was administered during organogenesis (the critical period of organ formation in early pregnancy)