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In high-alcohol-consuming rats, Ex4 microinfusions into NAcS and LDTg decreased ethanol intake without affecting general behavior

The search strategy combines Medical Subject Headings (MeSH) and keywords including GLP-1, glucagon-like peptide-1 receptor, GLP-1 receptor agonist, sepsis, systemic inflammation, infection, immune response, critical illness, MODS, multiple organ dysfunction, cytokines and sepsis treatment. Articles were screened for relevance based on titles and abstracts, with full-text evaluation of studies addressing the mechanistic or therapeutic implications of GLP-1 signaling in experimental or clinical models of sepsis

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Tirzepatide, the active ingredient in Eli Lilly's Zepbound and diabetes injection Mounjaro, likely won't be eligible for those negotiations until the end of the decade.