wegovy semaglutide or tirzepatide Outperforms in Reducing Major Adverse Cardiovascular Events Weight loss drugs like Mounjaro

Switching from Ozempic to Zepbound In some circumstances, it might be preferable to transition from Ozempic to Zepbound, particularly for those patients, who have been taking Ozempic for off-label to lose weight and it is not very effective

Plan for the long term Weight maintenance after initial loss typically requires continued medication, potentially at a lower dose

Data showed more Wegovy users stopping treatment because of them than Mounjaro users

That is the honest read of the 2025 tirzepatide vs semaglutide evidence, and it is why EASO 2025 guidelines treat both drugs as first-line with tirzepatide favored for obesity without CV disease