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A combined genetic score showed up to a 30% difference in HbA1c reduction be-tween low- and high-response carriers, highlighting the clinical relevance of these variants, though effects were specific to GLP-1 receptor agonists and not other drug classes
However, the most affected area is the last section of the small intestine (ileum) or the large intestine (colon)
Well-controlled hypothyroidism shouldnt significantly impact how well Wegovy works
Perhaps more impressively, 89-93% of participants achieved less than 5% liver fat content, which is the threshold for being considered free of fatty liver disease
