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Furthermore, leptin receptor-deficient mice, a mouse model of obesity and diabetes, and people with endogenous glucagon deficiency (pancreatectomised individuals) treated with glucagon antisense oligonucleotide have increased hepatic fat [52, 53]

As such, increasing GLP-1 levels naturally, often by prioritizing foods containing high amounts of protein and fiber, has become increasingly popular in those looking to manage weight and cravings

Supplementary Materials Data Availability Statement The data that support the findings of this study were obtained from the TriNetX Research Network, a federated, multi-institutional clinical research platform that provides access to de-identified electronic health record data

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