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synaptophysin (MO 776) from Leica (Newcastle, UK), insulin (I-2018) from Sigma (Buchs, Switzerland), glucagon from Sigma (Buchs, Switzerland), somatostatin from Dako (Baar, Switzerland), and PP (RP030) from Diagnostic BioSystem (Pleasanton, CA, USA)

Tirzepatide produced a significantly greater reduction in HbA1c compared to other OMMs, whereas liraglutide and semaglutide were associated with a greater reduction of FPG in contrast to the other OMMs (Table 1)

GLP-1 therapy can be effective when hormonal and metabolic shifts are the main drivers of the weight gain

for instance, there is an enhanced propensity for carbohydrate intake in hyperinsulinemic hypoglycemic patients [64]