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Leptin and gene therapy Leptin has been recognized as one of the therapeutic candidates for obesity and as a regulator of fat mass, but its therapeutic effect is limited because of the apparent development of leptin resistance and the decreased BBB transport that is, observed in obese subjects with elevated blood leptin levels

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Both medications are highly effective, but Tirzepatides dual-hormone mechanism (GLP-1 + GIP) may lead to faster or more significant weight-loss results for some individuals