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Description
In addition to PanNETs, duodenal NETs show high prevalence of GLP- 1R expression

JAMA 2021;325:1414-1425

"Often, it's something that may have a marginal pathway towards approval, or a really long time toward approval." The patient had been treated with tirzepatide Lilly's own dual-agonist obesity drug, sold as Zepbound, which the FDA approved in 2023 for approximately a year but achieved only moderate weight loss, according to sources familiar with the matter

The hypothalamic-pituitary-ovarian axis, which governs reproductive function, is sensitive to energy availability
