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In the PIONEER 1 trial , which evaluated Rybelsus as monotherapy in treatment-nave patients, the 7 mg dose reduced HbA1c by approximately 0.91.2% (9.813.1 mmol/mol) from baseline, whilst the 14 mg dose achieved reductions of approximately 1.21.4% (13.115.3 mmol/mol) over 26 weeks

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Ozenoxacin has been shown to be bactericidal against S aureus and S pyogenes organisms
