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The overexpression of SGLT-2 was observed in pancreatic cancer cells (Scafoglio et al., 2015)

2025;24: e70094.

This effect may be explained by a DPP-4 inhibitor-dependent reduction in intestinal lipoprotein production and consecutive lowering of circulating chylomicrons ( Side Effects of DPP-4 Inhibitors DPP-4 inhibitors have shown good safety- and tolerability profiles in the phase III clinical study programs and the most frequent adverse events observed were nasopharyngitis and skin lesions

A single employee on Wegovy costs the plan roughly $12,000 to $16,000 per year
