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Poorly controlled diabetes in pregnancy increases the maternal risk for diabetic ketoacidosis, preeclampsia, spontaneous abortions, preterm delivery, and delivery complications

Patients with type 2 diabetes and obesitythe primary populations receiving tirzepatidehave multiple independent risk factors for acute pancreatitis that exist regardless of medication use

and speaker honoraria from AstraZeneca, Corcept Therapeutics, Merck and Novo Nordisk

Side effects improve significantly over time Second Natures research showed that side effects decrease substantially as the body adjusts to the medication: 3 Nausea dropped from 31.5% to 3.1% (semaglutide) and 27.8% to 10.5% (tirzepatide) by month 12 Fatigue dropped from 24.6% to 3.1% (semaglutide) and 21.5% to 8.1% (tirzepatide) by month 12 The proportion reporting no side effects increased significantly in both groups Hair loss: what the research shows Hair loss is often reported as a concern with weight-loss medications