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Experimental studies have also pointed to a direct ICP-lowering effect of GLP-1RAs

[DOI] [PMC free article] [PubMed] [Google Scholar] 64.Nauck M.A., Meier J.J

Furthermore, in the SURPASS-1 and -2 studies, a significant reduction in TG by 18.524.8%, in low-density lipoprotein cholesterol (LDL-C) by 5.212.4%, and in very low-density lipoprotein (VLDL)-cholesterol by 17.523.7%, as well as a significant increase of high-density lipoprotein cholesterol (HDL-C) by 3.27.9% were confirmed (Frias et al

Furthermore, the data from a phase II study in participants with obesity and MASH presented at the American Diabetes Association showed those on survodutide achieved 18.7% mean weight loss after 46 weeks compared to the placebo group
