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Mann JFE, Fonseca V, Mosenzon Oet al
This manufacturing difference has profound quality implications: Impurity profile: Recombinant yeast-expressed semaglutide has a characteristic fermentation-related impurity profile host cell proteins (HCPs), host cell DNA, and process-related impurities from fermentation

Its oral variant, Oral Wegovy, provides a convenient, needle-free option

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