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From weekly injections to a daily pill

The jury is out at the moment, but their potential to be differentiated from injectable peptides is clear and seems likely to drive significant research into small molecule modulators of GLP-1 for the treatment of diabetes, obesity and perhaps addictive behaviours for many years to come.

The review will adhere to the methodology outlined in the Joanna Briggs Institute Reviewers Manual [2], and will be reported in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses extension for Scoping Reviews (PRISMA-ScR) [8]

however, different from the above-cited papers, the main focus of this systematic review and NMA was to provide the basis for a management algorithm for the use of OMMs approved in European countries, specifically focusing on obesity-related complications