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Description
EP45 displays potent, concerted, independent agonism at both the GLP1-R and NPY2R
Additionally, blockade of GLP-1Rs in the LS with exendin-9 alone enhanced sucrose and oil intake indicating a physiologic role for these neurons to suppress food intake
It slows gastric emptying, meaning food sits in the stomach longer and satiety signals reach the brain sooner
Side Effects of GLP-1 Receptor Agonists
