glp-1 skin side effects Oh, Oh, Oh, Psoriasis: Impact of GLP-1s on Disease in South Jersey GLP-1RA & Inflammatory Skin Diseases

Description

Lancet (London, England) 2020;396(10258):12231249

59% were males

14.6% of the participants qualified for participation based on elevated filling pressures, 13.4% based on hospitalization for heart failure within 12 months in combination with ongoing diuretic treatment or echocardiographic abnormalities (or both), and 72.0% based on NT-proBNP levels plus echocardiographic abnormalities Median body weight and BMI of participants were 105.1 kg and 37.0kg/m 2 , respectively At baseline, patients had substantial degree of heart failure related symptoms, physical limitations, and poor exercise tolerance Outcomes Primary Outcome Co-primary endpoints for Semaglutide vs placebo from baseline to week 52: Change in KCCQ-CSS 16.6 points vs 8.7 points (estimated difference, 7.8 points