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[DOI] [PubMed] [Google Scholar] 31.Farilla L, Hui H, Bertolotto C, Kang E, Bulotta A, Di Mario U, et al
The dissociated Epac2 then dimerizes with Rim2 and Piccolo in a Ca 2+ -dependent manner followed by induction of exocytosis of the insulin granules through binding of the Epac2/Rim2/Piccolo complex to Rab3 which is located at the membrane of the insulin granules (Figure 6) [508,511]
Abiraterone acetate plus prednisone in patients with newly diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial
That gradual escalation is not just a technical detail
