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Description
To get a therapeutic effect, patients have to macro-dose, leading to severe GI distress
"The smoking cessation aids varenicline (marketed as Chantix) and bupropion (marketed as Zyban and generics) suicidal ideation and behavior" (PDF)
Shoutout to my amazing hubby for keeping me motivated and my boys for keeping me on my toes (seriously, how do 5- and 9-year-olds have this much energy?)
Discussion It has been widely accepted that class B1 GPCRs adopt a two-step model for ligand binding and receptor activation 34,43
