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Patients are advised to: Stop smoking smoking impairs circulation and worsens nerve damage Limit alcohol intake excessive alcohol is directly neurotoxic Maintain a healthy weight obesity contributes to poor glycaemic control Engage in regular exercise improves circulation and glucose metabolism Practice meticulous foot care daily inspection, appropriate footwear, and prompt treatment of injuries For symptomatic relief of painful diabetic neuropathy , NICE recommends a stepwise approach to pharmacological treatment

Additionally, this umbrella review focused only on comparisons between GLP-1 RAs and placebos or non-GLP-1 RA drugs, without directly comparing the efficacy among different GLP-1 RAs

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While its not a replacement for safer sex practices or regular medical monitoring, it can complement these efforts where appropriate