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"Implementing therapies that demonstrate [cardiovascular]-kidney benefits, and especially those that can change the trajectory of kidney function decline must be prioritized as a primary [cardiovascular disease] optimization strategy." Clinical Topics: Cardiovascular Care Team, Heart Failure and Cardiomyopathies, Acute Heart Failure Keywords: Diabetes Mellitus, Type 2, Renal Insufficiency, Chronic, Semaglutide, Heart Failure

28 Moreover, research involving more diverse Japanese populations, beyond the trial informed cohorts used in the present analysis, will be important to ensure generalizability across demographic and clinical characteristics

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Supplements like Chromium, Omega-3 fatty acids, and Coenzyme Q10 also help improve insulin resistance and weight loss
