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While GLP-1 receptor expression in the liver is debated among researchers, these medications appear to influence liver health through both direct and indirect mechanisms
Normally this would not be too much of an issue, but when combined with high temperatures in the summer, this can lead to severely impaired heat loss mechanisms from the body leading to heatstroke
Both medications can cause gastrointestinal symptoms, though through different mechanisms
Also, muscle loss can occur without showing up on a regular scale, leading to feelings of weakness or tiredness that might be hard to explain
