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EASL-EASD-EASO clinical practice guidelines on the management of metabolic dysfunction-associated steatotic liver disease (MASLD)

Bolinder J, Ljunggren , Kullberg J, et al

Incretin therapy in type 1 diabetes is rising in prevalence, but occasionally we are asking as healthcare providers, "What happens if I stop the medication?" We (myself with the support of Ahmad Haidar and Michael Tsoukas) decided to perform a post-hoc analysis of our double-blinded crossover trial to assess the effects of semaglutide withdrawal on insulin requirements, carb input and CGM metrics in participants who were assigned to semaglutide first, then placebo second in the trial

When patients are weaker going into rehabdue to GLP-1-induced muscle lossthey often experience: Slower progress Increased soreness Difficulty returning to previous activity levels 3