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Hunter BR, Wang AZ, Bucca AW, Musey PI Jr, Strachan CC, Roumpf SK, Propst SL, Croft A, Menard LM, Kirschner JM (2022) Efficacy of benzodiazepines or antihistamines for patients with acute vertigo: a systematic review and meta-analysis

This activation mobilizes stored triglycerides within hepatocytes for oxidation, effectively decreasing hepatic lipid content ( de novo lipogenesis while promoting lipid catabolism, resulting in a net reduction of hepatic steatosis ( In summary, this dual mechanism addresses the fundamental lipid dysregulation in MASLD by restoring the balance between lipid synthesis and degradation within the liver, thereby mitigating steatosis and its metabolic consequences ( 3.2.3 Anti-inflammatory and anti-fibrotic effects Activation of GLP-1 receptors by dual agonists exerts potent anti-inflammatory effects within the liver microenvironment, which are crucial for preventing progression from steatosis to steatohepatitis and fibrosis

Semaglutide, on the other hand, focuses on enhancing GLP-1 activity, providing similar benefits in weight management and blood sugar regulation

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