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Research progress on the mechanism of beta-cell apoptosis in type 2 diabetes mellitus

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INTRODUCTION The incretin hormones secreted by L cells in the ileum and colon are GLP-1 receptor agonists (RAs) [3]

Keywords: glucagon-like peptide 1 receptor agonists, semaglutide, salivary glands, xerostomia, cyclic AMP, beta-arrestins Abstract This review addresses the growing concern of oral side effects, particularly dry mouth, associated with semaglutide, a glucagon-like peptide-1 receptor agonist (GLP-1RA) widely used for diabetes and obesity