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The potential role of GLP-1 agonists in treating alcohol use disorder (AUD) has emerged from both animal studies and early-phase human trials, though it is important to emphasise that there is no official licence for these medications in AUD treatment in the UK or elsewhere

For most people it eases within a few days to a couple of weeks, and about 75% see gastrointestinal side effects clear within four weeks at a stable dose

A post hoc calculation of reduction in overall mass (fat mass plus lean body mass) in the DXA substudy indicated reductions of 5.7 kg vs 4.1 kg for semaglutide and canagliflozin, respectively

Phentermine can cause jitteriness, increased heart rate, difficulty sleeping, and elevated blood pressure