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Description
Common effects include nausea, vomiting, and GI discomfort during the first 12 weeks, which typically resolve as your body adapts
Both TRIUMPH1 and TRIUMPH2 are basket trials with a nested OSA trial within each that includes participants who have moderatetosevere sleep apnea with or without exposure to positive airway pressure therapy
Your provider should assess baseline GI symptoms, establish a slower titration schedule, and monitor for new or worsening bloating, diarrhea, or abdominal pain at each dose increase
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