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A 2025 study of 200 adults combining GLP-1 medications with resistance training education and individualized protein intake (generally above 0.36 g/lb) showed participants lost approximately 13% of body weight but only 3% of muscle mass after six months

Wang L, Volkow ND, Berger NA, Davis PB, Kaelber DC, Xu R

Some patients report increased discomfort or irritation when injecting medication immediately after removing it from the refrigerator

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