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Conclusions The real-world evidence presented in this study supports findings from clinical trials such as SURPASS-2, emphasizing tirzepatides treatment effect over injectable semaglutide in reducing HbA1c and weight for patients with T2D

Coverage expansion is expected to continue through 2025, particularly within Medicaid programs and employer-sponsored health plans

Isothiocyanate-rich Moringa oleifera extract reduces weight gain, insulin resistance, and hepatic gluconeogenesis in mice

Drug pricing reform initiatives, particularly the Inflation Reduction Act in the United States which has introduced Medicare drug price negotiation, could create medium-term pricing pressure on branded semaglutide products that may indirectly compress API acquisition prices