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4 While MASLD is an umbrella term for hepatic steatosis (fat in the liver) in association with at least 1 metabolic risk factor (overweight or obesity, type 2 diabetes, dyslipidemia, hypertension), in MASH there is also hepatic inflammation and hepatocyte ballooning, with a high risk of progression and fibrosis
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TLR and NLRP3 inflammasome-dependent innate immune responses to tumor-derived autophagosomes (DRibbles)
