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In a randomised controlled trial with over 1800 participants comparing tirzepatide to semaglutide, the tirzepatide group reported more serious adverse events (5-7% VS 3%) and higher discontinuation rates due to adverse events (6-8.5% VS 4%)

The drug slows the movement of food from the stomach into the intestine, so you feel fuller after eating less food

In the Phase 3 ATTAIN-1 trial, adults with obesity taking the highest approved dose achieved an average weight loss of 12.4% at 72 weeks compared with approximately 0.9% with placebo

Lingvay I, Brown-Frandsen K, Colhoun HM, et al
