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The majority of these observations, summarized in Supplementary Table S1, are confirmed through extensive mutagenesis studies on GLP1-R and other Family B GPCRs 2031

Acknowledgements The authors gratefully thank Inge Timmermann, Bente Knap, Charlotte Kostecki, Karina G Larsen, Lone K Larsen, John Lind, Tina Cutherbertson, Trine Jessen and Lene Albaek for expert technical assistance

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