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For many patients, appetite signaling returns and weight regain is common after stopping

For people with insurance coverage, there are usually multiple hoops to jump through, and each insurance companys prior authorization requirements are different, says Allison Rhodes, MD, an internal medicine and obesity medicine physician at the Ohio State University Wexner Medical Center in Columbus

Phentermine-topiramate (Qsymia) Rather than mimicking hormones to turn off the brains hunger cues as GLP-1s do prescription phentermine-topiramate regulates what we call neurotransmitters, or signals directly in the brain, to alter appetite, says Kushner

Our competitor, Novo, then did a similar trick and made a weekly